Are 'Kenzan' and 'Ishin' Related as 'Yakuza' Game Spin-Offs?

Are "Yakuza Kenzan" and 'Like a Dragon: Ishin!' related? These two spin-offs take place at different points during the feudal era of Japan.
Are Yakuza Kenzan and 'Like a Dragon: Ishin!' related? These two spin-offs take place at different points during the feudal era of Japan.

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